Tags: Disease.
Distal renal tubular acidosis (dRTA) or Type 1 Renal tubular acidosis (RTA) is the classical form of RTA being the first described. Distal RTA is characterized by a failure of acid secretion by the alpha intercalated cells of the cortical collecting duct of the distal nephron. This failure of acid secretion may be due to a number of causes and it leads to an inability to acidify the urine to a pH of less than 5.3.