Tags: Drug.

Dirithromycin is a macrolide glycopeptide antibiotic.Dirithromycin (Dynabac) is a more lipid-soluble prodrug derivative of 9S-erythromycyclamine prepared by condensation of the latter with 2-(2-methoxyethoxy)acetaldehyde. The 9N 11O-oxazine ring thus formed is a hemi-aminal that is unstable under both acidic and alkaline aqueous conditions and undergoes spontaneous hydrolysis to form erythromycyclamine.

Dirithromycin.svg
ATC prefix
J01
ATC suffix
FA13
Bioavailability
10.0
CAS number
62013-04-1
ChEBI
474014
DrugBank
DB00954
FDA UNII code
1801D76STL
IUPAC name
(2R3R6R7S8S9R10R12R13S15R17S)-9-[(2S3R4S6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-3-ethyl-210-dihydroxy-7-[(2R4R5S6S)-5-hydroxy-4-methoxy-46-dimethyloxan-2-yl]oxy-15-[(2-methoxyethoxy)methyl]-268101217-hexamethyl-416-dioxa-14-azabicyclo[11.3.1]heptadecan-5-one
PubChem
6917067

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