Tags: Drug.
Diphenylpyraline (DPP; sold as Allergen Arbid Belfene Diafen Hispril Histyn Lergobine Lyssipol Mepiben Neargal) is a first-generation antihistamine with anticholinergic effects of the diphenylpiperidine class. It is marketed in Europe for the treatment of allergies. DPP has also been found to act as a dopamine reuptake inhibitor and produces hyperactivity in rodents. It has been shown to be useful in the treatment of Parkinsonism.