Tags: Protein.
Deoxyribonuclease I (usually called DNase I) is an endonuclease coded by the human gene DNASE1.DNase I is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide yielding 5′-phosphate-terminated polynucleotides with a free hydroxyl group on position 3′ on average producing tetranucleotides. It acts on single-stranded DNA double-stranded DNA and chromatin.