Tags: Chemical Compound, Chemical Substance.

DADLE ([D-Ala2 D-Leu5]-Enkephalin) is a synthetic opioid peptide with analgesic properties. Although it is often considered a selective delta opioid receptor agonist it also binds to the μ1 subtype of mu opioid receptors. Treatment with DADLE results in transient depression of mean arterial blood pressure and heart rate.Its peptide sequence is Tyr-D-Ala-Gly-Phe-D-Leu.

2-D-Alanine-5-D-leucine-enkephalin.png
IUPAC name
(2R)-2-(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid

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