Tags: Protein.
Cholesterol 24-hydroxylase is an enzyme that in humans is encoded by the CYP46A1 gene.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain where it converts cholesterol to 24S-hydroxycholesterol.