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Cytochrome P450 3A4 (abbreviated CYP3A4) (EC 1.14.13.97) is an important enzyme in the body mainly found in the liver and in the intestine. Its purpose is to oxidize small foreign organic molecules (xenobiotics) such as toxins or drugs so that they can be removed from the body.While many drugs are deactivated by CYP3A4 there are also some drugs which are activated by the enzyme. Some substances such as grapefruit juice and some drugs interfere with the action of CYP3A4.

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