Tags: Protein.
Cycle (cyc) is a gene in Drosophila melanogaster that encodes the CYCLE protein. The Cycle gene is expressed in a variety of cell types in a circadian manner. It is involved in controlling both the sleep-wake cycle and circadian regulation of gene expression by promoting transcription in a negative feedback mechanism. The cyc gene is located on the left arm of chromosome 3 and codes for a transcription factor containing a basic helix-loop-helix (bHLH) domain and a PAS domain.
