Tags: Protein.
The crotonase family comprises mechanistically diverse proteins that share a conserved trimeric quaternary structure (sometimes a hexamer consisting of a dimer of trimers) the core of which consists of 4 turns of a (beta/beta/alpha)n superhelix. Some enzymes in the superfamily have been shown to display dehalogenase hydratase and isomerase activities while others have been implicated in carbon-carbon bond formation and cleavage as well as the hydrolysis of thioesters.