Tags: Protein.
In molecular biology the creb binding domain is a protein domain. It is the interlocking domain of the eukaryotic nuclear receptor coactivators CREBBP and P300. This interlocking domain forms a 3-helical non-globular array that forms interlocked heterodimers with its target.Nuclear receptors are ligand-activated transcription factors involved in the regulation of many processes including development reproduction and homeostasis.