Tags: Drug.
Cotinine is an alkaloid found in tobacco and is also a metabolite of nicotine. The word cotinine is an anagram of nicotine. Cotinine is used as a biomarker for exposure to tobacco smoke and has also been sold as an antidepressant under the brand name Scotine.Similarly to nicotine cotinine binds to activates and desensitizes neuronal nicotinic acetylcholine receptors though at much lower potency in comparison. It has demonstrated nootropic and antipsychotic-like effects in animal models.
