Tags: Enzyme.
Costunolide synthase (EC 1.14.13.120) is an enzyme with system name germacra-1(10)411(13)-trien-12-oateNADPH:oxygen oxidoreductase (6alpha-hydroxylating). This enzyme catalyses the following chemical reaction germacra-1(10)411(13)-trien-12-oate + NADPH + H+ + O2 (+)-costunolide + NADP+ + 2 H2OCostunolide synthase is a heme-thiolate protein (P-450).