Tags: Protein.
Corneodesmosin is a protein that in humans is encoded by the CDSN gene.This gene encodes a protein found in corneodesmosomes which localize to human epidermis and other cornified squamous epithelia. During maturation of the cornified layers the protein undergoes a series of cleavages which are thought to be required for desquamation. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6.