Tags: Protein.
The contryphans (conus + tryptophan) are a family of peptides that are active constituents of the poisonous venom produced by cone snail (genus conus). The two amino acid cysteine residues in contryphans are linked by a disulfide bond. In addition contryphans undergo an unusual degree of post-translational modification including epimerization of leucine and tryptophan tryptophan bromination amidation of the C-terminus and proline hydroxylation.