Tags: Chemical Compound, Chemical Substance.
Conessine is a steroid alkaloid found in a number of plant species from the Apocynaceae family including Holarrhena floribunda Holarrhena antidysenterica and Funtumia elastica several of which are used in traditional herbal medicine as a treatment for amoebic dysentery. It acts as a histamine antagonist selective for the H3 subtype (with an affinity of pKi=8.27; Ki~5nM).
