Tags: Disease.
Clouston’s hidrotic ectodermal dysplasia (also known as Alopecia congenita with keratosis palmoplantaris Clouston syndrome Fischer–Jacobsen–Clouston syndrome Hidrotic ectodermal dysplasia Keratosis palmaris with drumstick fingers and Palmoplantar keratoderma and clubbing) is caused by mutations in a connexin gene GJB6 or connexin-30 characterized by scalp hair that is wiry brittle and pale often associated with patchy alopecia.