Clotiazepam (marketed under brand name Clozan Distensan Trecalmo Rize Rizen and Veratran) is a thienodiazepine drug which is a benzodiazepine analog. The clotiazepam molecule differs from most other benzodiazepines in that the benzene ring has been replaced by a thiophene ring. It possesses anxiolytic skeletal muscle relaxant anticonvulsant sedative properties. Stage 2 NREM sleep is significantly increased by clotiazepam.
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