Tags: Protein.

H(+)/Cl(-) exchange transporter 5 is a protein that in humans is encoded by the CLCN5 gene.This gene encodes a member of the ClC family of chloride ion channels and ion transporters. Mutations in this gene have been found in Dent’s Disease and renal tubular disorders complicated by nephrolithiasis. Although a member of a family of chloride channels the CLCN5 protein allows movement of protons in the opposite direction of Cl(-) thus functioning as an antiporter.

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