Tags: Protein.
Neuronal acetylcholine receptor subunit alpha-4 is a protein that in humans is encoded by the CHRNA4 gene.The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. After binding acetylcholine these pentameric receptors respond by undergoing an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.