Tags: Drug.
Chlorcyclizine (Di-Paralene Mantadil Pruresidine Trihistan) is a first-generation antihistamine of the phenylpiperazine class marketed in the United States and certain other countries. It is used primarily to treat allergy symptoms such as rhinitis urticaria and pruritus and may also be used as an antiemetic. In addition to its antihistamine effects chlorcyclizine also has some anticholinergic antiserotonergic and local anesthetic properties.