The Chemins de Fer Ottomans d’Anatolie (Turkish: Osmanlı Anadolu Demiryolları English: Anatolian Railway) was an Ottoman railway founded on October 4 1888. The railway was headquartered in İstanbul.The CFOA was the busiest railway in the Ottoman Empire and was one of the two railways operating into İstanbul along with the Chemins de fer Orientaux.