Tags: Protein.
In molecular biology the Cfr10I/Bse634I family of restriction endonucleases includes the type II restriction endonucleases Cfr10I and Bse634I. They exhibit a conserved tetrameric architecture that is of functional importance wherein two dimers are arranged back-to-back with their putative DNA-binding clefts facing opposite directions. These clefts are formed between two monomers that interact mainly via hydrophobic interactions supported by a few hydrogen bonds to form a U-shaped dimer.
