Tags: Protein.
In molecular biology the CFC domain (Cripto_Frl-1_Cryptic domain) is a protein domain found at the C-terminus of a number of proteins including Cripto (or teratocarcinoma-derived growth factor). It is structurally similar to the C-terminal extracellular portions of Jagged 1 and Jagged 2. CFC is approx 40-residues long compacted by three internal disulphide bridges and binds Alk4 via a hydrophobic patch.
