Cdc4 (cell division control protein 4) is a substrate recognition component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex which acts as a mediator of ubiquitin transfer to target proteins leading to their subsequent degradation via the ubiquitin-proteasome pathway. Cdc4 targets primarily cell cycle regulators for proteolysis. It serves the function of an adaptor that brings target molecules to the core SCF complex.
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EntrezGene
850539
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Archipelago homolog (hAgo), Cdc4, Egg laying defective protein 41, F-box and WD-40 domain-containing protein 7, F-box protein FBX30, F-box/WD repeat-containing protein sel-10, Fbw7, SEL-10, Suppressor/enhancer of lin-12 protein 10, cell division control protein 4, hCdc4
