Tags: Protein.
Inducible T-cell costimulator is a protein that in humans is encoded by the ICOS gene.CD278 or ICOS (Inducible T-cell COStimulator) is a CD28-superfamily costimulatory molecule that is expressed on activated T cells. It is thought to be important for Th2 cells in particular.The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling immune responses and regulation of cell proliferation.