Tags: Protein.
In molecular biology the Cbl TKB domain (tyrosine kinase binding domain) also known as the phosphotyrosine binding (PTB) domain is a conserved region found at the N-terminus of Cbl adaptor proteins. This N-terminal region is composed of three evolutionarily conserved domains: an N-terminal four-helix bundle domain an EF hand-like domain and a SH2-like domain which together are known to bind to phosphorylated tyrosine residues.
