Tags: Protein.
Protein CBFA2T3 is a protein that in humans is encoded by the CBFA2T3 gene.The t(16;21)(q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5′-region of the AML1 gene fused to the 3′-region of this gene. In addition this gene is a putative breast tumor suppressor.