List of articles in "Drug" category - Page 90

Naranol (W-5494A) is an antidepressant anxiolytic and antipsychotic with a tricyclic-like chemical structure which was synthesized in the late 1960s but was never marketed.

Mezepine is a tricyclic antidepressant (TCA) that was never marketed.

Lortalamine (LM-1404) is an antidepressant which was synthesized in the early 1980s. It acts as a potent and highly selective norepinephrine reuptake inhibitor. Lortalamine was under development for clinical use […]

Homopipramol is a tricyclic antidepressant (TCA) with neuroleptic properties which was never marketed.

Mariptiline (EN-207) is a tricyclic antidepressant (TCA) which was developed in the early 1980s but was never marketed.

JWH-161 is a cannabinoid derivative that was designed by Dr John W. Huffman’s team as a hybrid between the dibenzopyran classical cannabinoid drugs and the novel indole derivatives in an […]

Linaclotide (marketed under the trade name Linzess and Constella) is an peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients […]

CI-1017 is a muscarinic acetylcholine receptor agonist which is selective for and is approximately equipotent at the M1 and M4 receptors with 20-30-fold lower affinity for the M2 M3 and […]

Talsaclidine (WAL-2014) is a non-selective muscarinic acetylcholine receptor agonist which acts as a full agonist at the M1 subtype and as a partial agonist at the M2 and M3 subtypes.

Mapracorat (INN code names BOL-303242-X ZK 245186) is an anti-inflammatory drug belonging to the experimental class of selective glucocorticoid receptor agonists (SEGRAs). It is in clinical trials for the topical […]