TROX-1 is a drug which acts as a potent blocker of the Cav2 type calcium channels. It was developed as a potential analgesic after the discovery that the selective Cav2.2 […]
List of articles in "Drug" category - Page 85
PRX-08066
PRX-08066 is a drug discovered and developed by Predix (later Epix) Pharmaceuticals [Dale S. Dhanoa et al. Patent US 7030240 B2] which acts as a potent and selective antagonist at […]
Cariprazine
Cariprazine (RGH-188) is an antipsychotic drug by Gedeon Richter. It acts as a D2 and D3 receptor partial agonist with high selectivity towards the D3 receptor. Positive Phase III study […]
Poractant alfa
Poractant alfa is a pulmonary surfactant sold under the brand name Curosurf by Chiesi Farmaceutici. Poractant alfa is an extract of natural porcine lung surfactant.
Insulin degludec
Insulin degludec is an ultralong-acting basal insulin analogue being developed by Novo Nordisk under the brand name Tresiba. It is administered via subcutaneous injection. It can be given daily or […]
PCCG-4
PCCG-4 is a research drug which acts as a selective antagonist for the group II metabotropic glutamate receptors (mGluR2/3) with slight selectivity for mGluR2 although not sufficient to distinguish mGluR2 […]
Cobicistat
Cobicistat (formerly GS-9350) is a licensed drug for use in the treatment of infection with the human immunodeficiency virus (HIV).Like ritonavir (Norvir) cobicistat is of interest for its ability to […]
Prosultiamine
Prosultiamine (Alinamin Binova Jubedel Taketron Thiobeta Thiotiamina) also known as thiamine propyl disulfide (TPD) is a disulfide thiamine derivative developed in Japan in the 1950s as a treatment for vitamin […]
Fursultiamine
Fursultiamine (INN; Adventan Alinamin-F Benlipoid Bevitol Lipophil Judolor) also known as thiamine tetrahydrofurfuryl disulfide (TTFD) is a disulfide derivative of thiamine or an allithiamine. It was synthesized in Japan in […]
Ro5-4864
Ro5-4864 (4′-Chlorodiazepam) is a drug which is a benzodiazepine derivative the 4′-chloro derivative of diazepam. However unlike most benzodiazepine derivatives Ro5-4864 lacks affinity for GABAA receptors and lacks typical benzodiazepine […]