Ispronicline (TC-1734 AZD-3480) is a drug which acts as a partial agonist at neural nicotinic acetylcholine receptors. It is subtype-selective binding primarily to the α4β2 subtype. It has antidepressant nootropic […]
List of articles in "Drug" category - Page 248
Dichloropane
Dichloropane ((-)-2β-Carbomethoxy-3β-(34-dichlorophenyl)tropane RTI-111 O-401) is a powerful SNDRI with IC50 (nM) values of 0.79 3.13 and 18 at the DAT SERT and NET.Methylecgonidine as the direct precursor to this compound.In […]
Diclofensine
Diclofensine (Ro 8-4650) is a stimulant drug which acts as a triple monoamine reuptake inhibitor primarily inhibiting the reuptake of dopamine and norepinephrine with affinities (Ki) of 16.8nM 15.7nM and […]
Betamipron
Betamipron (INN) or N-benzoyl-β-alanine is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity.
Panipenem
Panipenem (INN) is a carbapenem antibiotic used in combination with betamipron.
Neticonazole
Neticonazole (INN) is an imidazole antifungal for the treatment of fungal skin infections.Neticonazole is only approved for use in Japan. It is sold as a topical ointment under the tradename […]
Flesinoxan
Flesinoxan (DU-29373) is a potent and selective 5-HT1A receptor partial/near-full agonist of the phenylpiperazine class. Originally developed as an antihypertensive agent it was later found to possess antidepressant and anxiolytic […]
Casopitant
Casopitant (trade names Rezonic (US) Zunrisa (EU)) is an neurokinin 1 (NK1) receptor antagonist undergoing research for the treatment of chemotherapy-induced nausea and vomiting (CINV). It is currently under development […]
Benzbromarone
Benzbromarone (INN) is a uricosuric agent and non-competitive inhibitor of xanthine oxidase used in the treatment of gout especially when allopurinol a first-line treatment fails or produces intolerable adverse effects.
Butyltolylquinuclidine
2-Butyl-3-(p-tolyl)quinuclidine (BTQ) is a stimulant DRI. It is one of a number of substituted quinuclidine derivatives developed as potential medications for the treatment of cocaine abuse and produces similar effects […]