The ANTH domain is a membrane binding domain that shows weak specificity for PtdIns(45)P2. It was found in AP180 (a.k.a. CALM) endocytotic accessory protein that has been implicated in the […]
List of articles in "Biomolecule" category - Page 1652
BAR domain
BAR (Bin–Amphiphysin–Rvs) domains are highly conserved protein dimerisation domains that occur in many proteins involved in membrane dynamics in a cell. The BAR domain is banana shaped and binds to […]
Bruton’s tyrosine kinase
Bruton’s tyrosine kinase (abbreviated Btk or BTK) is a type of kinase enzyme implicated in the primary immunodeficiency disease X-linked agammaglobulinemia (Bruton’s agammaglobulinemia). Its exact mechanism of action remains unknown […]
Interleukin 11
Interleukin 11 (IL-11) is a protein that in humans is encoded by the IL11 gene.IL-11 is a multifunctional cytokine first isolated in 1990 from bone marrow-derived stromal cells. It is […]
Collagen type XXVII alpha 1
Collagen alpha-1 (XXVII) chain (COL27A1) is a protein that in humans is encoded by the COL27A1 gene.COL27A1 is a type XXVII collagen. It was discovered by James Pace. This gene […]
Protein kinase R
Protein kinase RNA-activated also known as protein kinase R (PKR) interferon-induced double-stranded RNA-activated protein kinase or eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) is an enzyme that in humans […]
Orotidine 5′-phosphate decarboxylase
Orotidine 5’-phosphate decarboxylase (OMP decarboxylase) or orotidylate decarboxylase is an enzyme involved in pyrimidine biosynthesis. It catalyzes the decarboxylation of orotidine monophosphate (OMP) to form uridine monophosphate (UMP). The function […]
Azoospermia factor
Azoospermia factor (AZF) refers to one of several proteins or their genes which are coded from the AZF region on the human male Y chromosome. Deletions in this region are […]
Aspartokinase
Aspartokinase or aspartate kinase is an enzyme that catalyzes the phosphorylation of the amino acid aspartate. This reaction is the first step in the biosynthesis of three essential amino acids: […]
DUF1220
DUF1220 is a protein domain of unknown function that shows a striking human lineage-specific (HLS) increase in copy number and may be important to human brain evolution. The copy number […]