Tags: Drug.

Caspofungin (INN) (brand name Cancidas worldwide) is a lipopeptide antifungal drug from Merck & Co. Inc.. It is a member of a new class of antifungals termed the echinocandins. It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall. Caspofungin was the first inhibitor of fungal (1→3)-β-D-glucan synthesis to be approved by the United States Food and Drug Administration.Caspofungin is administered intravenously.

Caspofungin.svg
ATC prefix
J02
ATC suffix
AX04
Bioavailability
100.0
CAS number
179463-17-3
DrugBank
DB00520
FDA UNII code
VUW370O5QE
IUPAC name
N-[(3S6S9S11R15S18S20R21R24S25S)-3-[(1R)-3-amino-1-hydroxypropyl]-21-[(2-aminoethyl)amino]-6-[(1S2S)-12-dihydroxy-2-(4-hydroxyphenyl)ethyl]-112025-trihydroxy-15-[(1R)-1-hydroxyethyl]-258141723-hexaoxo-147131622-hexaazatricyclo[22.3.0.0913]heptacosan-18-yl]-1012-dimethyltetradecanamide
PubChem
468682

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