Tags: Protein.

CASP8-associated protein 2 is a protein that in humans is encoded by the CASP8AP2 gene.This protein is highly similar to FLASH a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor Fas-binding adapter FADD and caspase 8 and plays a regulatory role in Fas-mediated apoptosis.

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