Tags: Protein.
Calpain-3 is a protein that in humans is encoded by the CAPN3 gene.Calpain a heterodimer consisting of a large and a small subunit is a major intracellular protease although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A.