Tags: Protein.
Calnexin (CNX) is a 67kDa integral protein (that appears variously as a 90kDa 80kDa or 75kDa band on western blotting depending on the source of the antibody) of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain a single transmembrane helix and a short (90 residues) acidic cytoplasmic tail.