Calcitriol (INN) /kælˈsɪtri.ɒl/ also called 125-dihydroxycholecalciferol or 125-dihydroxyvitamin D3 is the hormonally active form of vitamin D with three hydroxyl groups (abbreviated 125-(OH)2D3 or simply 125(OH)2D) It was first identified by Michael F. Holick in work published in 1971. Calcitriol increases the level of calcium (Ca2+) in the blood by increasing the uptake of calcium from the gut into the blood and possibly increasing the release of calcium into the blood from bone.
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