Tags: Protein.
The human gene Chromosome 3 open reading frame 14 is a gene of uncertain function located at 3p14.2 near fragile site FRBA3—which falls between this gene and the centromere. Its protein is expected to localize to the nucleus and bind DNA. Orthologs have been identified in all of the major animal groups minus amphibians and insects tracing as far back as the sea anemone; indicating an origin of over 1000 mya highlighting its importance in the animal genome.