Tags: Chemical Compound, Chemical Substance.
Butyrophenone is a chemical compound; some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia as well as acting as antiemetics.Butyrophenones are a class of pharmaceutical drugs derived from butyrophenone.Examples include: Haloperidol the most widely used classical antipsychotic drug in this class Droperidol often used for neuroleptanalgesic anesthesia and sedation in intensive-care treatment Benperidol the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine) Triperidol a highly potent antipsychotic (100 times more potent than chlorpromazine) Melperone a weakly potent antipsychotic in Europe commonly used for treatment of insomnia confusional states psychomotor agitation and delirium in particular in geriatric patients Lenperone azaperone used in veterinary medicine Domperidone a dopamine-antagonist antiemetic derived further from butyrophenone (not being a butyrophenone itself).The atypical antipsychotic risperidone although not a butyrophenone was developed with the structures of benperidol and ketanserin as a basis.
