Tags: Drug.
BU-48 is a drug that is used in scientific research. It is from the oripavine family related to better-known drugs such as etorphine and buprenorphine. The parent compound from which BU-48 was derived (with N-methyl rather than methylcyclopropyl on the nitrogen and lacking the aliphatic hydroxyl group) is a powerful μ-opioid agonist 1000x more potent than morphine but in contrast BU-48 has only weak analgesic effects and instead acts primarily as a δ-opioid agonist.
