Tags: Protein.
The BRICHOS family consists of a variety of proteins linked to major diseases each containing a 100 amino acid BRICHOS domain that is thought to have a chaperone function.These include BRI2 which is related to familial British and Danish dementia (FBD and FDD); Chondromodulin-I related to chondrosarcoma; CA11 related to stomach cancer; and surfactant protein C (SP-C) related to respiratory distress syndrome (RDS).