Tags: Protein.
Nucleosome-remodeling factor subunit BPTF is a protein that in humans is encoded by the BPTF gene.This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer’s disease. Analysis of the original protein (fetal Alz-50 reactive clone 1 or FAC1) identified as an 810 aa protein containing a DNA-binding domain and a zinc finger motif suggested it might play a role in the regulation of transcription.