Tags: Enzyme.

Heparanase (EC 3.2.1.166 Hpa1 heparanase Hpa1 heparanase 1 heparanase-1 C1A heparanase HPSE) is an enzyme with system name heparan sulfate N-sulfo-D-glucosamine endoglucanase. This enzyme catalyses the following chemical reaction endohydrolysis of (1->4)-beta-D-glycosidic bonds of heparan sulfate chains in heparan sulfate proteoglycanHeparanase cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or a 6-O-sulfo group.

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