Tags: Chemical Compound, Chemical Substance.
BINAP (22′-bis(diphenylphosphino)-11′-binaphthyl) is an organophosphorus compound. This chiral ligand is widely used in asymmetric synthesis. It consists of a pair of 2-diphenylphosphinonaphthyl groups linked at the 1 and 1´ positions. This C2-symmetric framework lacks a stereogenic atom but has axial chirality due to restricted rotation (atropisomerism). The barrier to racemization is high due to steric hindrance which limits rotation about the bond linking the naphthyl rings.
