Tags: Drug.

Betrixaban (INN codenamed PRT-054021) is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is potent orally active and highly selective for factor Xa being selected from a group of similar compounds for its low hERG affinity. Betrixaban has undergone human clinical trials for prevention of embolism after knee surgery and prevention of stroke following atrial fibrillation with promising results.Joint development with Portola was discontinued in 2011 by Merck.

Betrixaban_structure.png
ATC prefix
none
CAS number
330942-05-7
FDA UNII code
74RWP7W0J9
IUPAC name
N-(5-chloropyridin-2-yl)-2-([4-(NN-dimethylcarbamimidoyl)benzoyl]amino)-5-methoxybenzamide
PubChem
10275777

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