Tags: Drug.
BD1060 or N-[2-(34-dichlorophenyl)ethyl]-1-pyrrolidineethanamine is a selective sigma receptor antagonist with a reported binding affinity of Ki = 3 ± 0.1 nM for the sigma-1 receptor and greater than 50 times selectivity over the sigma-2 receptor.Like other sigma receptor antagonists pretreating Swiss Webster mice with BD1060 significantly reduces the behavioral toxicity of cocaine.
