Tags: Drug.
BD1052 or N-[2-(34-dichlorophenyl)ethyl]-N-2-propen-1-yl-1-pyrrolidineethanamine is a selective sigma receptor agonist with a reported binding affinity of Ki = 2 ± 0.5 nM for the sigma-1 receptor and 30 times selectivity over the sigma-2 receptor.Consistent with other reported sigma receptor agonists pretreating Swiss Webster mice with BD1052 significantly increases the behavioral toxicity of cocaine.