Tags: Protein.
Apoptosis regulator Bcl-2 is a family of evolutionarily related proteins. These proteins govern mitochondrial outer membrane permeabilization (MOMP) and can be either pro-apoptotic (Bax BAD Bak and Bok among others) or anti-apoptotic (including Bcl-2 proper Bcl-xL and Bcl-w among an assortment of others). There are a total of 25 genes in the Bcl-2 family known to date.