Tags: Protein.
In molecular biology barrier-to-autointegration factor (BAF) is a family of essential proteins that is highly conserved in metazoan evolution and which may act as DNA-bridging proteins. BAF binds directly to double-stranded DNA to transcription activators and to inner nuclear membrane proteins including lamin A filament proteins that anchor nuclear pore complexes in place and nuclear LEM-domain proteins that bind to laminins filaments and chromatin.