Tags: Protein.
The B-cell linker protein is encoded by the BLNK gene and is an adaptor protein also known as SLP-65 BASH and BCA. BLNK is expressed in B cells and macrophages and plays a large role in B cell receptor signalling in a fashion analogous to the role its paralogue SLP-76 plays in T cell receptor signalling. As it has no known intrinsic enzymatic activity the function of BLNK is to temporally and spatially coordinate and regulate signalling effectors downstream of the B cell receptor.