Aztreonam (trade names Azactam injection Cayston inhalation) is a synthetic monocyclic beta-lactam antibiotic (a monobactam) with the nucleus based on a simpler monobactam isolated from Chromobacterium violaceum. It was approved by the U.S. Food and Drug Administration (FDA) in 1986. It is resistant to some beta-lactamases but is inactivated by extended-spectrum beta-lactamases.
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